⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276358 | 0.73 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL21987084 | 0.71 | — | — | |
| SCHEMBL4415548 | 0.69 | — | — | |
| SCHEMBL1777628 | 0.69 | — | — | |
| SCHEMBL2438019 | 0.67 | — | — | |
| SCHEMBL2444396 | 0.66 | — | — | |
| SCHEMBL27308533 | 0.65 | — | — | |
| SCHEMBL6008092 | 0.63 | — | — | |
| SCHEMBL2639486 | 0.61 | MGLL (0.50) | — | |
| SCHEMBL559604 | 0.60 | TP53 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394922-B | Preparation method of N-substituted pyrrolyl aryl propenone compound | 河南农业大学 | 2024-06-11 | — | — | CN | claimed |
| CN-114394922-A | Preparation method of N-substituted pyrrolyl aryl propenone compound | 河南农业大学 | 2022-04-26 | — | — | CN | claimed |
| CN-114213307-A | Preparation method of N-alkyl substituted pyrrolidone compound | 河南农业大学 | 2022-03-22 | — | — | CN | claimed |
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | claimed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | claimed |
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | claimed |
| US-4092474-A | Cephalosporins having a metaloxy group in 3-substituent | SHIONOGI & CO., LTD. (JA) | 1978-05-30 | — | — | US | claimed |
| CN-114394922-B | Preparation method of N-substituted pyrrolyl aryl propenone compound | 河南农业大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-114394922-B | Preparation method of N-substituted pyrrolyl aryl propenone compound | 河南农业大学 | 2024-06-11 | — | — | CN | disclosed |
| US-20230143246-A1 | LIQUID PREPARATIONS OF AMINES AND ORGANIC ACIDS STABILIZED BY SALTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20230088365-A1 | PROCESS FOR PRODUCING PYRROLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-03-23 | — | — | US | disclosed |
| CN-115141131-A | 3,4-diacetyl-2,5-dimethylpyrrole compound and preparation method and application thereof | 湖北中烟工业有限责任公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114835619-A | Process for preparing azole compounds | 武田药品工业株式会社 | 2022-08-02 | — | — | CN | disclosed |
| US-4199519-A | TREATMENT OF PEPTIC ULCERS | SANKYO COMPANY LIMITED (JP) | 1980-04-22 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4151357-A | FOR PEPTIC ULCERS | SANKYO COMPANY LIMITED (JP) | 1979-04-24 | — | — | US | disclosed |
| US-4150224-A | BACTERICIDES | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1979-04-17 | — | — | US | disclosed |
| US-4145538-A | 3-Carbamyloxymethyl-cephalosporins | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |