Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699322 | 0.78 | MGLL (0.46) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL379033 | 0.78 | MAOA (0.47) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL34594 | 0.76 | MGLL (0.56) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL17070868 | 0.74 | MGLL (0.48) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL366266 | 0.72 | MGLL (0.65) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL14678413 | 0.71 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL114195 | 0.71 | MGLL (0.58) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL145737 | 0.71 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL19514746 | 0.71 | MGLL (0.70) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL278150 | 0.71 | CHRM2 (0.52) | MGLLFAAHALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257606-A1 | PREPARATION AND USE OF ANTI-FSHR ANTIBODY AND ANTIBODY-DRUG CONJUGATE THEREOF | Canwell (GZ) Biotech Limited (CN) | 2023-10-11 | — | — | EP | claimed |
| CN-114605542-A | anti-FSHR antibody, preparation method and application of antibody-drug conjugate thereof | 康威(广州)生物科技有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-110643032-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-110643032-A | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2020-01-03 | — | — | CN | claimed |
| JP-4732331-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| US-7521531-B2 | Methods for the purification of stable radioiodine conjugates | IMMUNOMEDICS, INC. (US) | 2009-04-21 | — | — | US | claimed |
| EP-1592476-B1 | METHODS FOR THE PURIFICATION OF STABLE RADIOIODINE CONJUGATES | IMMUNOMEDICS INC (US) | 2007-04-11 | — | — | EP | claimed |
| EP-1592476-A1 | METHODS FOR THE PURIFICATION OF STABLE RADIOIODINE CONJUGATES | Immunomedics, Inc. (US) | 2005-11-09 | — | — | EP | claimed |
| US-6858705-B2 | Stable radioiodine conjugates and methods for their synthesis | IMMUNOMEDICS, INC. (US) | 2005-02-22 | — | — | US | claimed |
| US-6818742-B1 | FOR IN VIVO RADIOIMMUNODETECTION/DIAGNOSIS/THERAPY OF CANCER/TUMORS | IMMUNOMEDICS, INC. | 2004-11-16 | — | — | US | claimed |
| WO-2004071571-A1 | METHODS FOR THE PURIFICATION OF STABLE RADIOIODINE CONJUGATES | IMMUNOMEDICS, INC. (US) | 2004-08-26 | — | — | WO | claimed |
| US-20040086454-A1 | Stable radioiodine conjugates and methods for their synthesis | IMMUNOMEDICS, INC. | 2004-05-06 | — | — | US | claimed |
| US-20030220470-A1 | Methods for the purification of stable radioiodine conjugates | IMMUNOMEDICS, INC. | 2003-11-27 | — | — | US | claimed |
| CN-118105511-A | Antibody coupling drug and preparation method and application thereof | 浙江大学 | 2024-05-31 | — | — | CN | disclosed |
| US-20240115648-A1 | HYDROPHILIC ANTIBODY-DRUG CONJUGATES | SEAGEN INC (US) | 2024-04-11 | — | — | US | disclosed |
| US-20240043548-A1 | PREPARATION AND USE OF ANTI-FSHR ANTIBODY AND ANTIBODY-DRUG CONJUGATE THEREOF | CANWELL (GZ) BIOTECH LIMITED (CN) | 2024-02-08 | — | — | US | disclosed |
| US-6858705-B2 | Stable radioiodine conjugates and methods for their synthesis | IMMUNOMEDICS, INC. (US) | 2005-02-22 | — | — | US | disclosed |
| US-6818742-B1 | FOR IN VIVO RADIOIMMUNODETECTION/DIAGNOSIS/THERAPY OF CANCER/TUMORS | IMMUNOMEDICS, INC. | 2004-11-16 | — | — | US | disclosed |
| US-20040086454-A1 | Stable radioiodine conjugates and methods for their synthesis | IMMUNOMEDICS, INC. | 2004-05-06 | — | — | US | disclosed |
| US-4560648-A | CONJUGATED THROUGH THIO GROUP OF B-GALACTOSIDASE | SYNTEX (U.S.A.) INC. (US) | 1985-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043548-A1 | PREPARATION AND USE OF ANTI-FSHR ANTIBODY AND ANTIBODY-DRUG CONJUGATE THEREOF | FSHR, GNRHR, SHBG | MGLL 4804/4885FAAH 2177/4885ALDH1A1 4414/4885 |
| US-20240115648-A1 | HYDROPHILIC ANTIBODY-DRUG CONJUGATES | CD44, FCGR1A, FCGR2A | MGLL 3217/4885FAAH 1248/4885ALDH1A1 535/4885 |
| US-20040086454-A1 | Stable radioiodine conjugates and methods for their synthesis | PTMS, DNPEP, ANPEP | MGLL 3249/4885FAAH 2426/4885ALDH1A1 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.