Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 16/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 16/20 | 0.56 |
| ▸ | PRKAB1 | Q9Y478 | 16/20 | 0.56 |
| ▸ | PTGES | O14684 | 2/20 | 0.51 |
| ▸ | HMGCR | P04035 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825906 | 1.00 | PRKAG1 (0.56) | PRKAG1PRKAA2PRKAB1PTGESHMGCR | |
| SCHEMBL30222239 | 1.00 | PRKAG1 (0.56) | PRKAG1PRKAA2PRKAB1PTGESHMGCR | |
| SCHEMBL22498515 | 0.88 | PRKAG1 (0.57) | PRKAG1PRKAA2PRKAB1HMGCR | |
| SCHEMBL19423484 | 0.86 | PRKAG1 (0.75) | PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL29825605 | 0.86 | PRKAG1 (0.75) | PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL19423486 | 0.85 | PRKAG1 (0.60) | PRKAG1PRKAA2PRKAB1HMGCR | |
| SCHEMBL18824044 | 0.85 | PRKAG1 (0.60) | PRKAG1PRKAA2PRKAB1HMGCR | |
| SCHEMBL29980010 | 0.83 | PRKAG1 (0.53) | PRKAG1PRKAA2PRKAB1PTGES | |
| SCHEMBL5576927 | 0.81 | PTGES (0.43) | PRKAG1PRKAA2PRKAB1PTGESHMGCR | |
| SCHEMBL6274473 | 0.78 | PTGES (0.80) | PTGESHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283844-A1 | METHODS OF PRODUCING MOGROSIDES AND COMPOSITIONS COMPRISING SAME AND USES THEREOF | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2017-10-05 | — | — | US | disclosed |