Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189940 | 0.84 | ALDH1A1 (0.33) | POLBAPAF1GRK2DNMT1PTPN7 | |
| SCHEMBL5415901 | 0.84 | APAF1 (0.31) | POLBAPAF1GRK2DNMT1PTPN7 | |
| SCHEMBL5415894 | 0.84 | APAF1 (0.31) | POLBAPAF1GRK2DNMT1PTPN7 | |
| SCHEMBL19620188 | 0.82 | POLB (0.31) | DPP4POLBAPAF1GRK2DNMT1 | |
| SCHEMBL3264994 | 0.82 | APAF1 (0.31) | POLBAPAF1GRK2DNMT1PTPN7 | |
| SCHEMBL23559897 | 0.81 | CA1 (0.33) | POLBAPAF1GRK2DNMT1PTPN7 | |
| SCHEMBL19222188 | 0.81 | POLB (0.31) | POLBAPAF1GRK2DNMT1PTPN7 | |
| SCHEMBL12086458 | 0.79 | CA1 (0.37) | POLBGRK2L3MBTL1 | |
| SCHEMBL469511 | 0.79 | CA1 (0.37) | POLBGRK2L3MBTL1 | |
| SCHEMBL19851439 | 0.79 | CA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283537-A1 | Stable Polymeric Nanoparticle Compositions and Methods Related Thereto | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-10-05 | — | — | US | disclosed |