Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942417 | 0.84 | CCR2 (0.49) | CCR2IGF1RNR3C2SCN9AMEN1 | |
| SCHEMBL3931756 | 0.82 | CCR2 (0.53) | CCR2IGF1RNR3C2SCN9AMEN1 | |
| SCHEMBL3900906 | 0.75 | NR3C2 (0.46) | CCR2IGF1RNR3C2ACACBACACA | |
| SCHEMBL1941172 | 0.74 | PKM (0.52) | CCR2IGF1RSCN9AMEN1KMT2A | |
| SCHEMBL10239425 | 0.74 | CCR2 (0.60) | CCR2IGF1RNR3C2SCN9AMEN1 | |
| SCHEMBL1943028 | 0.74 | PTPRC (0.48) | CCR2IGF1RSCN9AKMT2ANPSR1 | |
| SCHEMBL19968761 | 0.74 | SCN9A (0.47) | CCR2IGF1RNR3C2SCN9AMEN1 | |
| SCHEMBL1941006 | 0.74 | CCR2 (0.52) | CCR2IGF1RSCN9AMEN1KMT2A | |
| SCHEMBL1941340 | 0.74 | KDR (0.62) | CCR2MEN1KMT2ALMNATSHR | |
| SCHEMBL1941059 | 0.74 | KDR (0.49) | CCR2SCN9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1717229-B1 | NOVEL CYCLIC COMPOUND HAVING 4-PYRIDYLALKYLTHIO GROUP HAVING (UN)SUBSTITUTED AMINO INTRODUCED THEREIN | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-06-15 | — | — | EP | disclosed |
| EP-1717229-A1 | NOVEL CYCLIC COMPOUND HAVING 4-PYRIDYLALKYLTHIO GROUP HAVING (UN)SUBSTITUTED AMINO INTRODUCED THEREIN | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | EP | disclosed |