Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941310 | 0.89 | KDM4E (0.36) | PTGER4BRD4LMNASMN1; SMN2NPC1 | |
| SCHEMBL1943175 | 0.89 | LMNA (0.33) | PTGER4BRD4LMNASMN1; SMN2NPC1 | |
| SCHEMBL1943290 | 0.80 | ALDH1A1 (0.37) | PTGER4LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1942717 | 0.79 | MAPT (0.33) | PTGER4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1943217 | 0.77 | PTGER4 (0.44) | PTGER4BRD4LMNASMN1; SMN2NPC1 | |
| SCHEMBL1942639 | 0.71 | ACKR3 (0.36) | PTGER4LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4574787 | 0.69 | MEN1 (0.33) | LMNAMEN1KMT2AALDH1A1CDK9 | |
| SCHEMBL1942719 | 0.69 | MGAT2 (0.31) | — | |
| SCHEMBL1942293 | 0.68 | TSHR (0.38) | PTGER4LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1942259 | 0.68 | PTGER4 (0.35) | PTGER4BRD4LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466166-B2 | Benzimidazole derivatives as selective acid pump inhibitors | RAQUALIA PHARMA INC. (JP) | 2013-06-18 | — | — | US | disclosed |
| EP-2081939-B1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RAQUALIA PHARMA INC (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-20100048532-A1 | Benzimidazole Derivatives as Selective Acid Pump Inhibitors | RAQUALIA PHARMA INC. (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048532-A1 | Benzimidazole Derivatives as Selective Acid Pump Inhibitors | HRH2, HRH4, HRH1 | PTGER4 39/4885BRD4 252/4885LMNA 4475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.