SCHEMBL194281

SCHEMBL194281

O=Cc1cccc2cccnc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.54
MMP2 P08253 2/20 0.54
TSHR P16473 2/20 0.54
HSP90AA1 P07900 2/20 0.54
LMNA P02545 2/20 0.54
CCR1 P32246 2/20 0.54
CCR5 P51681 2/20 0.54
CCR8 P51685 2/20 0.54
MAPT P10636 2/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MMP9 P14780 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
MMP8 P22894 1/20 0.54
THPO P40225 1/20 0.54
MTOR P42345 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28278303 0.98 KDM4E (0.52) KDM4EMMP2TSHRHSP90AA1LMNA
SCHEMBL27822917 0.98 KDM4E (0.52) KDM4EMMP2TSHRHSP90AA1LMNA
Alcohol SCHEMBL28833538 0.89 NPC1 (0.54) KDM4EMMP2TSHRHSP90AA1LMNA
Quinoline SCHEMBL29291034 0.89 ALDH1A1 (0.57) KDM4EMMP2TSHRHSP90AA1LMNA
SCHEMBL27591438 0.83 KDM4E (0.50) KDM4EMMP2TSHRHSP90AA1LMNA
SCHEMBL6851776 0.81 BACE1 (0.49) KDM4EMMP2TSHRHSP90AA1LMNA
SCHEMBL30630250 0.81 BACE1 (0.49) KDM4EMMP2TSHRHSP90AA1LMNA
SCHEMBL6851779 0.81 BACE1 (0.49) KDM4EMMP2TSHRHSP90AA1LMNA
SCHEMBL29875444 0.81 LMNA (0.50) KDM4EMMP2TSHRHSP90AA1LMNA
SCHEMBL24060233 0.79 KDM4E (0.54) KDM4EMMP2TSHRHSP90AA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119976881-A Preparation method of dual-function MCM-41 molecular sieve for adsorbing and detecting aluminum ions 辽宁工业大学 2025-05-13 CN claimed
CN-119823172-A Quinoline skeleton-based [ NN ] bidentate coordination metal catalyst and preparation method and application thereof 辽宁石油化工大学 2025-04-15 CN claimed
CN-119462775-A Quinoline imine palladium complex, preparation method and application thereof 链行走新材料科技(广州)有限公司 2025-02-18 CN claimed
CN-119320349-A Quinoline acylhydrazone ligand, fe (II) spin cross complex thereof and synthesis method thereof 南京理工大学 2025-01-17 CN claimed
CN-113164458-B Monoacylglycerol lipase modulators 詹森药业有限公司 2024-09-13 CN claimed
CN-118619879-A Preparation method and application of trifluoromethyl substituted enaminone 浙江理工大学 2024-09-10 CN claimed
CN-117205211-B Application of quinoline compound in preparation of fish parasitic protozoan resisting medicine 西北农林科技大学深圳研究院 2024-04-05 CN claimed
CN-114836201-B Zinc ion-mediated fluorescence sensor and preparation method and application thereof 哈尔滨理工大学 2024-01-26 CN claimed
CN-117205211-A Application of quinoline compound in preparation of fish parasitic protozoan resisting medicine 西北农林科技大学深圳研究院 2023-12-12 CN claimed
CN-117126181-A Trifluoromethyl phenylthiourea-quinoline copper complex with tumor autophagy induction effect, and preparation method and application thereof 河南城建学院 2023-11-28 CN claimed
CN-1168633-A Boronic ester and acid compounds, their synthesis and use PROSCRIPT INC (US) 1997-12-24 CN claimed
EP-0788360-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES PROSCRIPT, INC. (US) 1997-08-13 EP claimed
WO-1997016433-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1997-05-09 WO claimed
WO-1996031527-A1 PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES BOEHRINGER INGELHEIM (CANADA) LTD./BOEHRINGER INGELHEIM (CANADA) LTÉE. (CA) 1996-10-10 WO claimed
US-5545640-A VIRICIDES, HIV; AIDS BIO-MEGA/BOEHRINGER INGELEHEIM RESEARCH INC. (CA) 1996-08-13 US claimed
WO-1996013266-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES PROSCRIPT, INC. (US) 1996-05-09 WO claimed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US claimed
EP-0399394-A1 8-Azolylmethylquinolines BASF Aktiengesellschaft (DE) 1990-11-28 EP claimed
US-4426306-A Antioxidants and lubricating oil containing same STANDARD OIL COMPANY (INDIANA) (US) 1984-01-17 US claimed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US claimed