Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19429657 | 0.78 | NPC1 (0.41) | SMN1; SMN2ATMBRD4ALDH1A1KMT2A | |
| SCHEMBL19429624 | 0.73 | KDM4E (0.43) | SMN1; SMN2ATMBRD4ALDH1A1PDE4D | |
| SCHEMBL29626163 | 0.70 | KDM4E (0.42) | SMN1; SMN2ATMALDH1A1EGLN1L3MBTL1 | |
| SCHEMBL19377597 | 0.70 | KDM4E (0.42) | SMN1; SMN2ATMALDH1A1EGLN1L3MBTL1 | |
| SCHEMBL23370712 | 0.69 | FEN1 (0.39) | SMN1; SMN2ATMBRD4ALDH1A1NPC1 | |
| SCHEMBL19377934 | 0.69 | GRIA1 (0.50) | SMN1; SMN2ATMALDH1A1KMT2ATSHR | |
| SCHEMBL29626177 | 0.69 | GRIA1 (0.50) | SMN1; SMN2ATMALDH1A1KMT2ATSHR | |
| SCHEMBL19429626 | 0.69 | FEN1 (0.39) | SMN1; SMN2ATMBRD4ALDH1A1NPC1 | |
| SCHEMBL28681776 | 0.69 | ALDH1A1 (0.43) | SMN1; SMN2ATMALDH1A1NPC1TP53 | |
| SCHEMBL19403731 | 0.69 | KDM4E (0.40) | SMN1; SMN2ATMBRD4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172596-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORPORATION (US) | 2017-10-05 | — | — | WO | disclosed |