Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 18/20 | 0.55 |
| ▸ | EED | O75530 | 2/20 | 0.52 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.52 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.52 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.45 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19430324 | 0.98 | EZH2 (0.54) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL19429913 | 0.96 | EZH2 (0.56) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684233 | 0.94 | EZH2 (0.62) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12498796 | 0.88 | EZH2 (0.62) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684232 | 0.87 | EZH2 (0.63) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12683918 | 0.87 | EZH2 (0.62) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12683971 | 0.87 | EZH2 (0.68) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12684194 | 0.85 | EZH2 (0.67) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL19429879 | 0.84 | KDM5B (0.44) | EZH2 | |
| SCHEMBL12683973 | 0.84 | EZH2 (0.63) | EZH2EEDRBBP4SUZ12RBBP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | PRMT1, PRMT3, PRMT5 | EZH2 28/4885EED 745/4885RBBP4 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.