Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 10/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19421641 | 0.86 | KDM5B (0.50) | KDM5BEZH2RAB9AL3MBTL1 | |
| SCHEMBL19430325 | 0.84 | EZH2 (0.55) | EZH2 | |
| SCHEMBL19429795 | 0.83 | RAB9A (0.41) | KDM5BEZH2RAB9AL3MBTL1 | |
| SCHEMBL19430272 | 0.83 | KDM5B (0.48) | KDM5BEZH2RAB9AL3MBTL1 | |
| SCHEMBL19430261 | 0.82 | KDM5B (0.51) | KDM5BEZH2RAB9AL3MBTL1 | |
| SCHEMBL19430125 | 0.82 | KDM5B (0.53) | KDM5BEZH2RAB9A | |
| SCHEMBL19430324 | 0.82 | EZH2 (0.54) | EZH2 | |
| SCHEMBL19430263 | 0.81 | KDM5B (0.49) | KDM5BEZH2RAB9AL3MBTL1 | |
| SCHEMBL19429855 | 0.81 | KDM5B (0.46) | KDM5BEZH2RAB9AL3MBTL1 | |
| SCHEMBL19430136 | 0.81 | RAB9A (0.40) | KDM5BEZH2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | PRMT1, PRMT3, PRMT5 | KDM5B 147/4885EZH2 28/4885RAB9A 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.