⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382220 | 0.97 | — | — | |
| SCHEMBL5244018 | 0.93 | — | — | |
| SCHEMBL5241067 | 0.86 | — | — | |
| SCHEMBL4365463 | 0.78 | CHRNA7 (0.37) | — | |
| SCHEMBL17025210 | 0.77 | CHRM5 (0.36) | — | |
| SCHEMBL378120 | 0.75 | MC4R (0.41) | — | |
| SCHEMBL4388036 | 0.73 | — | — | |
| SCHEMBL382662 | 0.73 | — | — | |
| SCHEMBL3640689 | 0.73 | — | — | |
| SCHEMBL11288832 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 792 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229205-A | Preparation method and pharmaceutical application of phenyl acrylamide RHbDD1 inhibitor | 中国医学科学院基础医学研究所 | 2023-12-15 | — | — | CN | claimed |
| EP-3952995-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | Riboscience LLC (US) | 2022-02-16 | — | — | EP | claimed |
| CN-114040915-A | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | 里伯赛恩斯有限责任公司 | 2022-02-11 | — | — | CN | claimed |
| WO-2020210649-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC (US) | 2020-10-15 | — | — | WO | claimed |
| CN-111514123-A | Application of ketorolac analogue in resisting virus infection | 江苏伯克生物医药股份有限公司 | 2020-08-11 | — | — | CN | claimed |
| US-9908892-B2 | Melampomagnolide B derivatives | BIOVENTURES, LLC (US) | 2018-03-06 | — | — | US | claimed |
| EP-3257848-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR ACTIVITY | Novartis AG (CH) | 2017-12-20 | — | — | EP | claimed |
| EP-2900637-B1 | THIAZOLE OR IMIDAZOLE SUBSTITUTED PYRIMIDINE, PYRIDINE AND PYRAZINE AMIDE DERIVATIVES AND RELATED COMPOUNDS AS ABL1, ABL2 AND BCR-ABL1 INHIBITORS FOR THE TREATMENT OF CANCER, SPECIFIC VIRAL INFECTIONS AND SPECIFIC CNS DISORDERS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | claimed |
| EP-2773635-B1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR ACTIVITY | NOVARTIS AG (CH) | 2017-08-02 | — | — | EP | claimed |
| EP-2731436-B1 | 2-(PYRROLO[2,3-B]PYRIDINE-5-YL)-2-(T-BUTOXY)-ACETIC ACID DERIVATIVES AS HIV REPLICATION INHIBITORS FOR THE TREATMENT OF AIDS | VIIV HEALTHCARE UK LTD (GB) | 2017-03-08 | — | — | EP | claimed |
| WO-2000027822-A2 | TRICYCLIC PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | claimed |
| WO-2000000481-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-06 | — | — | WO | claimed |
| WO-1999055898-A1 | ENZYMATIC RESOLVATION FOR OBTAINING A (-)-3,4-TRANS-DIARYLCHROMAN | NOVO NORDISK A/S (DK) | 1999-11-04 | — | — | WO | claimed |
| EP-0764150-B1 | PRODUCTION OF HYDROXYTHIOACETAMIDES AND USE THEREOF IN THE SYNTHESIS OF BENZOTHIOPHENES | LILLY CO ELI (US) | 1999-10-27 | — | — | EP | claimed |
| EP-0937056-A1 | A PROCESS FOR THE PREPARATION OF (-)-3,4-TRANS-DIARYLCHROMANS | NOVO NORDISK A/S (DK) | 1999-08-25 | — | — | EP | claimed |
| US-5925771-A | Process for the preparation of (-)-3,4-trans-diarylchromans | NOVO NORDISK A/S (DK) | 1999-07-20 | — | — | US | claimed |
| WO-1998018770-A1 | A PROCESS FOR THE PREPARATION OF (-)-3,4-TRANS-DIARYLCHROMANS | NOVO NORDISK A/S (DK) | 1998-05-07 | — | — | WO | claimed |
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | claimed |
| EP-0168288-B1 | Aminomethyl-6-furo-[3,4-c]pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1990-04-25 | — | — | EP | claimed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | claimed |