⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194338 | 0.97 | — | — | |
| SCHEMBL5244018 | 0.90 | — | — | |
| SCHEMBL5241067 | 0.83 | — | — | |
| SCHEMBL3955463 | 0.77 | FDPS (0.37) | — | |
| SCHEMBL6329689 | 0.75 | — | — | |
| SCHEMBL4365463 | 0.75 | CHRNA7 (0.37) | — | |
| SCHEMBL17025210 | 0.75 | CHRM5 (0.36) | — | |
| SCHEMBL18085480 | 0.73 | CHRNA7 (0.40) | — | |
| SCHEMBL19286390 | 0.73 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL19965987 | 0.73 | CHRNA7 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3952995-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | Riboscience LLC (US) | 2022-02-16 | — | — | EP | claimed |
| WO-2020210649-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC (US) | 2020-10-15 | — | — | WO | claimed |
| CN-111514123-A | Application of ketorolac analogue in resisting virus infection | 江苏伯克生物医药股份有限公司 | 2020-08-11 | — | — | CN | claimed |
| US-20190322676-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARM INC (US) | 2019-10-24 | — | — | US | claimed |
| WO-2018118838-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2018-06-28 | — | — | WO | claimed |
| US-9908892-B2 | Melampomagnolide B derivatives | BIOVENTURES, LLC (US) | 2018-03-06 | — | — | US | claimed |
| US-20160368929-A1 | MELAMPOMAGNOLIDE B DERIVATIVES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2016-12-22 | — | — | US | claimed |
| US-9469650-B2 | Melampomagnolide B derivatives | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2016-10-18 | — | — | US | claimed |
| US-9238640-B2 | Anti-inflammatory agents | RESVERLOGIX CORP. (CA) | 2016-01-19 | — | — | US | claimed |
| US-20150133444-A1 | MELAMPOMAGNOLIDE B DERIVATIVES | BIOVENTURES, LLC | 2015-05-14 | — | — | US | claimed |
| US-20010039285-A1 | Tetrahydroisoquinoline compounds as estrogen agonists/antagonists | CAMERON KIMBERLY O (US) | 2001-11-08 | — | — | US | claimed |
| EP-1113007-A1 | Tetrahydroisoquinoline compounds as estrogen agonists/antagonists | PFIZER INC. (US) | 2001-07-04 | — | — | EP | claimed |
| EP-0764150-B1 | PRODUCTION OF HYDROXYTHIOACETAMIDES AND USE THEREOF IN THE SYNTHESIS OF BENZOTHIOPHENES | LILLY CO ELI (US) | 1999-10-27 | — | — | EP | claimed |
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | claimed |
| US-5324736-A | Diphenylcyclopropyl analogs as antiestrogenic and antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-06-28 | — | — | US | claimed |
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | claimed |
| EP-0410358-A1 | Aromatic carboxylic acid amides, their preparation and their use as medicines | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | claimed |
| EP-0362695-A1 | Pyrrolocarbazole derivatives, processes for their preparation and their use as medicaments | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | claimed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | claimed |
| US-4558046-A | ANTIALLERGENS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1985-12-10 | — | — | US | claimed |