Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672256 | 0.95 | CHRM2 (0.83) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL11094422 | 0.90 | CHRM2 (0.75) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL19449778 | 0.90 | CHRM2 (0.75) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL6163688 | 0.87 | CHRM2 (0.71) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL10151325 | 0.87 | CHRM2 (0.71) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL9128842 | 0.87 | SMN1; SMN2 (0.89) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL7253505 | 0.86 | CHRM2 (0.70) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL415949 | 0.85 | CHRM2 (0.67) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| Hydrochloric Acid SCHEMBL2799203 | 0.85 | CHRM2 (0.68) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 | |
| SCHEMBL12332380 | 0.84 | CHRM2 (0.66) | CHRM2SMN1; SMN2KDM4ETHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752606-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-08-25 | — | — | US | claimed |
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-04-02 | — | — | US | claimed |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | claimed |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | CHRM2 2454/4885SMN1; SMN2 3002/4885KDM4E 3521/4885 |
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | CHRM2 2454/4885SMN1; SMN2 3002/4885KDM4E 3521/4885 |
| US-10752606-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | CHRM2 2454/4885SMN1; SMN2 3002/4885KDM4E 3521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.