Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 10/20 | 0.53 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | INPP5B | P32019 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29427947 | 0.84 | INPPL1 (0.57) | INPPL1INPP5ASRCCA1CA2 | |
| SCHEMBL842250 | 0.82 | INPPL1 (0.59) | INPPL1INPP5ASRCCA1CA2 | |
| SCHEMBL17308714 | 0.79 | INPPL1 (0.52) | INPPL1INPP5ASRCCA1CA2 | |
| SCHEMBL5705521 | 0.77 | INPPL1 (0.53) | INPPL1INPP5ASRCCA1CA2 | |
| SCHEMBL11039261 | 0.77 | INPPL1 (0.53) | INPPL1INPP5ASRCCA1CA2 | |
| SCHEMBL25217653 | 0.75 | INPPL1 (0.65) | INPPL1INPP5ASRCCA1CA2 | |
| SCHEMBL10681450 | 0.75 | INPPL1 (0.47) | INPPL1INPP5ASRCCA1CA2 | |
| SCHEMBL8386637 | 0.74 | INPPL1 (0.65) | INPPL1INPP5ASRCCA1CA2 | |
| SCHEMBL545311 | 0.74 | SOS1 (0.46) | ESR1ESR2KDM4ELMNAHSD17B10 | |
| SCHEMBL329313 | 0.73 | SRC (0.75) | INPPL1INPP5ASRCCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11085022-B2 | Inflammation-targeted neutrophil granulocyte drug delivery system and use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-08-10 | — | — | US | claimed |
| US-20170292113-A1 | INFLAMMATION-TARGETED NEUTROPHIL GRANULOCYTE DRUG DELIVERY SYSTEM AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2017-10-12 | — | — | US | claimed |
| US-11085022-B2 | Inflammation-targeted neutrophil granulocyte drug delivery system and use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-08-10 | — | — | US | disclosed |
| US-20170292113-A1 | INFLAMMATION-TARGETED NEUTROPHIL GRANULOCYTE DRUG DELIVERY SYSTEM AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2017-10-12 | — | — | US | disclosed |