SCHEMBL545311

SCHEMBL545311

Oc1ccc(Oc2ccc(O)c(F)c2)cc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 2/20 0.46
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B1 P14061 3/20 0.41
HSD17B2 P37059 3/20 0.41
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HSP90AA1 P07900 1/20 0.38
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7077805 0.89 LTA4H (0.54) SOS1
SCHEMBL11343698 0.83 ESRRA (0.45) SOS1LMNAHSP90AA1ESRRA
SCHEMBL12806604 0.83 ESR1 (0.47) SOS1ESR1ESR2MEN1KMT2A
SCHEMBL12732739 0.82 ESRRA (0.48) ESR1ESR2KDM4ELMNAHSD17B10
SCHEMBL459327 0.81 GAA (0.55) MEN1KMT2AKDM4ELMNAHSD17B10
SCHEMBL25696644 0.80 LTA4H (0.40) SOS1HSD17B1HSD17B2
SCHEMBL423469 0.79 ESR1 (0.41) ESR1ESR2HSD17B1HSD17B2KDM4E
SCHEMBL20639058 0.78 ALOX15 (0.43) ESR1ESR2HSD17B1HSD17B2KDM4E
SCHEMBL29107394 0.78 ESR1 (0.40) ESR1ESR2HSD17B1HSD17B2KDM4E
SCHEMBL13250517 0.78 GPR3 (0.46) ESR1ESR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 631 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1757634-B2 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER USING SAME IDEMITSU KOSAN CO (JP) 2022-05-25 EP claimed
CN-101624442-A Polycarbonate resin and electrophotographic photoreceptor using the same IDEMITSU KOSAN CO 2010-01-13 CN claimed
US-12596311-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2026-04-07 US disclosed
EP-4711852-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FUJIFILM Business Innovation Corp. (JP) 2026-03-18 EP disclosed
US-20260056482-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FUJIFILM BUSINESS INNOVATION CORP. (JP) 2026-02-26 US disclosed
US-20250244689-A1 POSITIVELY CHARGEABLE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2025-07-31 US disclosed
EP-4592756-A1 POSITIVELY CHARGEABLE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM Business Innovation Corp. (JP) 2025-07-30 EP disclosed
WO-2025023065-A1 POLYCARBONATE-POLYARYLATE RESIN, COATING COMPOSITION, MOLDED BODY, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR 出光興産株式会社 2025-01-30 WO disclosed
WO-2024224788-A1 RESIN, COPOLYMER, ELECTRONIC SUBSTRATE MATERIAL, RESIN COMPOSITION, COATING LIQUID COMPOSITION, CURED PRODUCT, FILM, SHEET, AND ELECTRONIC SUBSTRATE 出光興産株式会社 2024-10-31 WO disclosed
EP-4174108-B1 RESIN PARTICLE, TONER, DEVELOPER, DEVELOPER STORAGE CONTAINER, RESIN PARTICLE PRODUCING METHOD, TONER PRODUCING METHOD, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH CO LTD (JP) 2024-09-18 EP disclosed
US-20240288789-A1 RESIN PARTICLE, TONER, DEVELOPING AGENT, DEVELOPING AGENT ACCOMMODATING UNIT, METHOD OF MANUFACTURING RESIN PARTICLE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2024-08-29 US disclosed
US-4229565-A BY FORMATION OF THE ACYL CHLORIDE THEN POLYMERIZING TO FORM HIGH MOLECULAR WEIGHT, HEAT RESISTANT POLYESTERS UNION CARBIDE CORPORATION (US) 1980-10-21 US disclosed
EP-0014237-A2 Photosensitive coating composition and its use in the production of a negative resist image International Business Machines Corporation (US) 1980-08-20 EP disclosed
EP-0005858-A1 Preparation of polyarylates UNION CARBIDE CORPORATION (US) 1979-12-12 EP disclosed
US-4174457-A Carbamate UNIROYAL, INC. (US) 1979-11-13 US disclosed
US-4080408-A FIRE RETARDANTS UNIROYAL, INC. (US) 1978-03-21 US disclosed
US-4058568-A FIRE RETARDANT UNIROYAL, INC. (US) 1977-11-15 US disclosed
US-4009200-A FIREPROOFING POLYMERS UNIROYAL, INC. (US) 1977-02-22 US disclosed
US-3994988-A CONTAINERS, SEPARATORS, MEDICAL EQUIPMENT BAXTER LABORATORIES, INC. (US) 1976-11-30 US disclosed
US-3950451-A COUPLED PRODUCT OF ALKYLPHENOL AND PHENOL-FORMALDEHYDE-DIAMINE CONDENSATE ASAHI DENKA KOGYO K.K. (JA) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12596311-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus NR2E3, RB1, ALDH1A2 SOS1 3143/4885ESR1 1143/4885ESR2 869/4885
US-20260056482-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE GLRA1, GRK1, GFRA1 SOS1 2598/4885ESR1 3090/4885ESR2 2766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.