SCHEMBL842250

SCHEMBL842250

O=P(O)(O)Oc1ccc(O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 10/20 0.59
INPP5A Q14642 6/20 0.59
SRC P12931 2/20 0.50
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
INPP5B P32019 2/20 0.44
BLM P54132 1/20 0.44
AKT1 P31749 1/20 0.40
STS P08842 1/20 0.40
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705521 0.82 INPPL1 (0.53) INPPL1INPP5ASRCCA1CA2
SCHEMBL19435239 0.82 INPPL1 (0.53) INPPL1INPP5ASRCCA1CA2
SCHEMBL11039261 0.82 INPPL1 (0.53) INPPL1INPP5ASRCCA1CA2
SCHEMBL8386637 0.79 INPPL1 (0.65) INPPL1INPP5ASRCCA1CA2
SCHEMBL131227 0.79 SRC (0.62) INPPL1INPP5ASRCCA1CA2
SCHEMBL21585530 0.79 INPPL1 (0.55) INPPL1INPP5ASRCCA1CA2
SCHEMBL4190769 0.79 TYR (0.61) INPPL1INPP5ASRCCA1CA2
SCHEMBL329313 0.78 SRC (0.75) INPPL1INPP5ASRCCA1CA2
SCHEMBL11575621 0.77 ALDH1A1 (0.57) INPPL1INPP5A
SCHEMBL28420405 0.77 SRC (0.60) INPPL1INPP5ASRCCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2722101-B1 REVERSE-OSMOSIS MEMBRANE HAVING AN ULTRA-HYDROPHILIC PROTECTIVE LAYER AND METHOD FOR PRODUCING SAME LG CHEMICAL LTD (KR) 2018-10-24 EP claimed
US-8770414-B2 Reverse osmosis membrane including ultra-hydrophilic passivation layer and method of manufacturing the same LG CHEM, LTD. (KR) 2014-07-08 US claimed
EP-2722101-A2 REVERSE-OSMOSIS MEMBRANE HAVING AN ULTRA-HYDROPHILIC PROTECTIVE LAYER AND METHOD FOR PRODUCING SAME LG Chem, Ltd. (KR) 2014-04-23 EP claimed
US-20130284663-A1 REVERSE OSMOSIS MEMBRANE INCLUDING ULTRA-HYDROPHILIC PASSIVATION LAYER AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2013-10-31 US claimed
US-8142953-B2 Hydrophilic adjuvant LG CHEM, LTD. (KR) 2012-03-27 US claimed
US-20100167168-A1 Hydrophilic Adjuvant LG CHEM, LTD. (KR) 2010-07-01 US claimed
WO-2007069867-A1 HYDROPHILIC ADJUVANT LG CHEM, LTD (KR) 2007-06-21 WO claimed
EP-2722101-B1 REVERSE-OSMOSIS MEMBRANE HAVING AN ULTRA-HYDROPHILIC PROTECTIVE LAYER AND METHOD FOR PRODUCING SAME LG CHEMICAL LTD (KR) 2018-10-24 EP disclosed
US-8770414-B2 Reverse osmosis membrane including ultra-hydrophilic passivation layer and method of manufacturing the same LG CHEM, LTD. (KR) 2014-07-08 US disclosed
EP-2722101-A2 REVERSE-OSMOSIS MEMBRANE HAVING AN ULTRA-HYDROPHILIC PROTECTIVE LAYER AND METHOD FOR PRODUCING SAME LG Chem, Ltd. (KR) 2014-04-23 EP disclosed
US-20130284663-A1 REVERSE OSMOSIS MEMBRANE INCLUDING ULTRA-HYDROPHILIC PASSIVATION LAYER AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2013-10-31 US disclosed
US-8142953-B2 Hydrophilic adjuvant LG CHEM, LTD. (KR) 2012-03-27 US disclosed
US-20100167168-A1 Hydrophilic Adjuvant LG CHEM, LTD. (KR) 2010-07-01 US disclosed
WO-2007069867-A1 HYDROPHILIC ADJUVANT LG CHEM, LTD (KR) 2007-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100167168-A1 Hydrophilic Adjuvant CD44, CD74, LY96 INPPL1 311/4885INPP5A 1668/4885SRC 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.