Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919114 | 1.00 | STING1 (0.47) | STING1NPC1RAB9ACYP3A4 | |
| SCHEMBL22121334 | 0.92 | STING1 (0.50) | STING1CYP3A4 | |
| SCHEMBL30823045 | 0.91 | STING1 (0.56) | STING1CYP3A4 | |
| SCHEMBL29868209 | 0.88 | STING1 (0.49) | STING1CYP3A4 | |
| SCHEMBL29868591 | 0.88 | STING1 (0.49) | STING1CYP3A4 | |
| SCHEMBL22150385 | 0.85 | STING1 (0.49) | STING1CYP3A4 | |
| SCHEMBL22121390 | 0.84 | STING1 (0.57) | STING1CYP3A4 | |
| Bromide SCHEMBL19436508 | 0.84 | STING1 (0.49) | STING1 | |
| Bromide SCHEMBL28617201 | 0.84 | STING1 (0.49) | STING1 | |
| Bromide SCHEMBL28617199 | 0.84 | STING1 (0.49) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071514-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-06 | — | — | CN | disclosed |
| EP-3440076-A1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2019-02-13 | — | — | EP | disclosed |
| WO-2017175147-A1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-10-12 | — | — | WO | disclosed |