Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436966 | 1.00 | TLR9 (0.49) | TLR9KMT2AMEN1POLBHTT | |
| SCHEMBL19436967 | 0.81 | TLR9 (0.59) | TLR9KMT2AMEN1HTTMAPT | |
| SCHEMBL19436965 | 0.81 | TLR9 (0.59) | TLR9KMT2AMEN1HTTMAPT | |
| SCHEMBL12487115 | 0.72 | TLR9 (0.58) | TLR9KMT2AMEN1HTTMAPT | |
| SCHEMBL12487118 | 0.72 | TLR9 (0.58) | TLR9KMT2AMEN1HTTMAPT | |
| SCHEMBL2717007 | 0.70 | TMEM97 (0.68) | KMT2AMEN1POLBHTTMAPT | |
| SCHEMBL6111089 | 0.69 | MCHR1 (0.53) | KMT2AMEN1POLBHTTMAPT | |
| SCHEMBL6803885 | 0.69 | MAPT (0.69) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL3543581 | 0.67 | PRMT5 (0.59) | TLR9POLBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12094893 | 0.67 | HDAC1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176930-A1 | DIPHENYLACRYLIC ACID DERIVATIVES THAT PROMOTE BONE AND CARTILAGE GROWTH | EMORY UNIVERSITY (US) | 2017-10-12 | — | — | WO | claimed |