Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436967 | 1.00 | TLR9 (0.59) | TLR9ABCG2MEN1KMT2AMAPT | |
| SCHEMBL19436966 | 0.81 | TLR9 (0.49) | TLR9MEN1KMT2AMAPTHPGD | |
| SCHEMBL19436964 | 0.81 | TLR9 (0.49) | TLR9MEN1KMT2AMAPTHPGD | |
| SCHEMBL12487115 | 0.80 | TLR9 (0.58) | TLR9ABCG2MEN1KMT2AMAPT | |
| SCHEMBL12487118 | 0.80 | TLR9 (0.58) | TLR9ABCG2MEN1KMT2AMAPT | |
| SCHEMBL19436975 | 0.79 | MEN1 (0.51) | TLR9MEN1KMT2AMAPTHPGD | |
| SCHEMBL19436973 | 0.79 | MEN1 (0.51) | TLR9MEN1KMT2AMAPTHPGD | |
| SCHEMBL4653351 | 0.79 | MEN1 (0.53) | MEN1KMT2AMAPTMAOAMAOB | |
| SCHEMBL4653348 | 0.79 | MEN1 (0.53) | MEN1KMT2AMAPTMAOAMAOB | |
| SCHEMBL80568 | 0.76 | MAPT (0.53) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176930-A1 | DIPHENYLACRYLIC ACID DERIVATIVES THAT PROMOTE BONE AND CARTILAGE GROWTH | EMORY UNIVERSITY (US) | 2017-10-12 | — | — | WO | claimed |
| WO-2017176930-A1 | DIPHENYLACRYLIC ACID DERIVATIVES THAT PROMOTE BONE AND CARTILAGE GROWTH | EMORY UNIVERSITY (US) | 2017-10-12 | — | — | WO | disclosed |