Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436973 | 1.00 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2008010 | 0.80 | AR (0.64) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL10693625 | 0.80 | AR (0.64) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2008011 | 0.80 | AR (0.64) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL19436965 | 0.79 | TLR9 (0.59) | MEN1KMT2AALDH1A1MAPTAKR1C3 | |
| SCHEMBL19436967 | 0.79 | TLR9 (0.59) | MEN1KMT2AALDH1A1MAPTAKR1C3 | |
| SCHEMBL6379914 | 0.73 | TSHR (0.50) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL6379911 | 0.73 | TSHR (0.50) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL13744802 | 0.72 | AKR1C2 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL269614 | 0.72 | AKR1C3 (0.63) | MEN1KMT2AALDH1A1MAPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176930-A1 | DIPHENYLACRYLIC ACID DERIVATIVES THAT PROMOTE BONE AND CARTILAGE GROWTH | EMORY UNIVERSITY (US) | 2017-10-12 | — | — | WO | disclosed |