Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008011 | 1.00 | AR (0.64) | ARMAPTNPSR1ALDH1A1TDP1 | |
| SCHEMBL10693625 | 1.00 | AR (0.64) | ARMAPTNPSR1ALDH1A1TDP1 | |
| SCHEMBL7823815 | 0.83 | MAPT (0.52) | ARMAPTNPSR1ALDH1A1TDP1 | |
| SCHEMBL7823813 | 0.83 | MAPT (0.52) | ARMAPTNPSR1ALDH1A1TDP1 | |
| SCHEMBL13744802 | 0.81 | AKR1C2 (0.56) | ARMAPTNPSR1ALDH1A1CYP19A1 | |
| SCHEMBL19436973 | 0.80 | MEN1 (0.51) | ARMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL19436975 | 0.80 | MEN1 (0.51) | ARMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11504802 | 0.80 | AR (0.52) | ARMAPTNPSR1ALDH1A1TDP1 | |
| SCHEMBL19436969 | 0.80 | MAPT (0.52) | ARMAPTALDH1A1TDP1CYP19A1 | |
| SCHEMBL19436968 | 0.80 | MAPT (0.52) | ARMAPTALDH1A1TDP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960548-B2 | Keratinocyte growth factor receptor—tyrosine specific inhibitors for the prevention of cancer metastatis | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-06-14 | — | — | US | disclosed |