Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19440828 | 0.88 | KMT2A (0.51) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440869 | 0.87 | KMT2A (0.53) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440806 | 0.86 | KMT2A (0.51) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440816 | 0.86 | KMT2A (0.53) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19442518 | 0.85 | KMT2A (0.48) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440823 | 0.84 | KMT2A (0.50) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440824 | 0.84 | KMT2A (0.51) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440826 | 0.84 | KMT2A (0.51) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL17540239 | 0.84 | KMT2A (0.48) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440861 | 0.83 | KMT2A (0.47) | KMT2AMEN1MAPTHTR2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783510-B2 | Small molecule mediated transcriptional induction of E-cadherin | VANDERBILT UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |