Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19440878 | 0.87 | SMN1; SMN2 (0.47) | KMT2AMEN1RAB9AHDAC3HDAC1 | |
| SCHEMBL19440828 | 0.87 | KMT2A (0.51) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440833 | 0.87 | KMT2A (0.53) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19442518 | 0.84 | KMT2A (0.48) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440866 | 0.83 | KMT2A (0.49) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440887 | 0.82 | KMT2A (0.53) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL19440831 | 0.82 | KDM4E (0.60) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL17511052 | 0.82 | RAB9A (0.61) | KMT2AMEN1MAPTRAB9AKDM4E | |
| SCHEMBL19440806 | 0.81 | KMT2A (0.51) | KMT2AMEN1L3MBTL1MAPTUSP2 | |
| SCHEMBL17540238 | 0.80 | KMT2A (0.48) | KMT2AMEN1L3MBTL1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783510-B2 | Small molecule mediated transcriptional induction of E-cadherin | VANDERBILT UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |
| US-9783510-B2 | Small molecule mediated transcriptional induction of E-cadherin | VANDERBILT UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |