Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17511304 | 0.84 | HDAC3 (0.47) | HTR2ANPC1RAB9AMAPT | |
| SCHEMBL19440839 | 0.84 | KMT2A (0.51) | OPRM1OPRK1TMEM97SIGMAR1KDM4C | |
| SCHEMBL19440809 | 0.83 | NPC1 (0.56) | ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL19440851 | 0.82 | LMNA (0.46) | NPC1RAB9AMAPT | |
| SCHEMBL19442547 | 0.82 | RAF1 (0.43) | OPRM1OPRK1TMEM97SIGMAR1KDM4C | |
| SCHEMBL19440886 | 0.80 | NAMPT (0.47) | ALDH1A1DRD3NPC1RAB9A | |
| SCHEMBL19442496 | 0.80 | HIF1A (0.46) | HTR2ADRD3HTR2CNPC1RAB9A | |
| SCHEMBL19440801 | 0.80 | HDAC3 (0.47) | HTR2ANPC1RAB9AMAPT | |
| SCHEMBL19440867 | 0.79 | P2RX7 (0.49) | NPC1RAB9A | |
| SCHEMBL19440843 | 0.79 | HDAC1 (0.56) | OPRM1OPRK1TMEM97SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783510-B2 | Small molecule mediated transcriptional induction of E-cadherin | VANDERBILT UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |
| US-9783510-B2 | Small molecule mediated transcriptional induction of E-cadherin | VANDERBILT UNIVERSITY (US) | 2017-10-10 | — | — | US | disclosed |