Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367923 | 1.00 | CCNB2 (0.50) | CCNB2CDK1CCNB1CCNB3SLC29A1 | |
| SCHEMBL21139458 | 0.88 | SLC29A1 (0.54) | CCNB2CDK1CCNB1CCNB3SLC29A1 | |
| SCHEMBL13966415 | 0.87 | CCNB2 (0.52) | CCNB2CDK1CCNB1CCNB3SLC29A1 | |
| SCHEMBL13966421 | 0.86 | ADORA3 (0.50) | — | |
| SCHEMBL13975992 | 0.86 | ADORA3 (0.50) | — | |
| SCHEMBL13966414 | 0.86 | PI4KA (0.61) | SLC29A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21139430 | 0.86 | PI4KA (0.61) | SLC29A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL17371116 | 0.86 | PI4KA (0.61) | SLC29A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13975624 | 0.86 | PI4KA (0.61) | SLC29A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20434991 | 0.83 | SLC29A1 (0.48) | CCNB2CDK1CCNB1CCNB3SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498774-B1 | DUAL-ACTION COMPOUNDS TARGETING ADENOSINE A2A RECEPTOR AND ADENOSINE TRANSPORTER FOR PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES | ACADEMIA SINICA (TW) | 2017-10-11 | — | — | EP | disclosed |