Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.33 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874060 | 0.75 | — | — | |
| SCHEMBL30373183 | 0.75 | ALDH1A1 (0.46) | ALDH1A1ATMHPGDLMNARAB9A | |
| SCHEMBL2734881 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDNOD1 | |
| SCHEMBL2734865 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDNOD1 | |
| SCHEMBL14851229 | 0.74 | ALDH1A1 (0.40) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL14502551 | 0.74 | ALDH1A1 (0.47) | ALDH1A1ATMTSHRHPGDNOD1 | |
| SCHEMBL8407945 | 0.74 | ALDH1A1 (0.47) | ALDH1A1ATMTSHRHPGDNOD1 | |
| SCHEMBL14045336 | 0.73 | ALDH1A1 (0.38) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL1097461 | 0.73 | NOD1 (0.50) | ALDH1A1ATMTSHRHPGDNOD1 | |
| SCHEMBL4957809 | 0.73 | NOD1 (0.50) | ALDH1A1ATMTSHRHPGDNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3228325-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | Mersana Therapeutics, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |