Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19443709 | 1.00 | SLC6A3 (0.61) | SLC6A3SIGMAR1ACHEDRD2DRD3 | |
| SCHEMBL15647988 | 0.83 | CYP2D6 (0.66) | SIGMAR1ACHE | |
| SCHEMBL4931173 | 0.83 | CYP2D6 (0.66) | SIGMAR1ACHE | |
| SCHEMBL12725 | 0.81 | ACHE (0.66) | SLC6A3SIGMAR1ACHE | |
| SCHEMBL21197752 | 0.81 | SLC6A3 (0.61) | SLC6A3SIGMAR1ACHEDRD2DRD3 | |
| SCHEMBL25285380 | 0.81 | SLC6A3 (0.61) | SLC6A3SIGMAR1ACHEDRD2DRD3 | |
| SCHEMBL11205656 | 0.81 | ACHE (0.66) | SLC6A3SIGMAR1ACHE | |
| SCHEMBL12929 | 0.81 | ACHE (0.66) | SLC6A3SIGMAR1ACHE | |
| SCHEMBL7348929 | 0.81 | SLC6A3 (0.61) | SLC6A3SIGMAR1ACHEDRD2DRD3 | |
| SCHEMBL7348925 | 0.81 | SLC6A3 (0.61) | SLC6A3SIGMAR1ACHEDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744781-B1 | FENTANYL DERIVATIVES AS PH-DEPENDENT OPIOID RECEPTOR AGONISTS | CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2017-10-11 | — | — | EP | disclosed |