Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262875 | 1.00 | ROCK2 (0.39) | ROCK2PRKACAAKT3KLKB1TSHR | |
| SCHEMBL21371588 | 1.00 | ROCK2 (0.39) | ROCK2PRKACAAKT3KLKB1TSHR | |
| SCHEMBL19944875 | 0.89 | ERAP2 (0.42) | ROCK2KLKB1TSHR | |
| SCHEMBL19445643 | 0.88 | ALDH1A1 (0.43) | KLKB1TSHRMMP2HDAC1MEN1 | |
| SCHEMBL19445833 | 0.88 | KLKB1 (0.42) | KLKB1TSHRMMP2HDAC1KMT2A | |
| SCHEMBL12516946 | 0.88 | KLKB1 (0.42) | KLKB1TSHRMMP2HDAC1KMT2A | |
| SCHEMBL19944721 | 0.88 | ERAP2 (0.42) | KLKB1TSHRMMP2 | |
| SCHEMBL19945106 | 0.88 | ERAP2 (0.41) | — | |
| SCHEMBL21371597 | 0.87 | KLKB1 (0.41) | KLKB1TSHRMMP2HDAC1MEN1 | |
| SCHEMBL21371927 | 0.87 | KLKB1 (0.41) | KLKB1TSHRMMP2HDAC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |