Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445567 | 0.89 | MTNR1A (0.41) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL10198852 | 0.89 | MTNR1A (0.46) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL12515465 | 0.84 | MTNR1A (0.43) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL12444102 | 0.84 | MTNR1A (0.43) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19481560 | 0.84 | MTNR1A (0.39) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19445539 | 0.84 | MTNR1A (0.41) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL12515350 | 0.83 | MAPK14 (0.41) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL10268065 | 0.83 | MAPK14 (0.41) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL13351617 | 0.83 | HTT (0.40) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11947670 | 0.81 | MTNR1A (0.39) | MTNR1AMTNR1BSMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |