Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515246 | 0.90 | ALDH1A1 (0.51) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL15942787 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL13319564 | 0.82 | KMT2A (0.36) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12514989 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12515253 | 0.80 | HTR4 (0.57) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12515257 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12514986 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12518639 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL16285911 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12515266 | 0.77 | KDM4E (0.47) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |