Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18561604 | 0.96 | CTSL (0.46) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL21948727 | 0.91 | CTSL (0.46) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL22168426 | 0.91 | CTSL (0.50) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL8640188 | 0.87 | CTSL (0.57) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL11814690 | 0.87 | CTSL (0.57) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL2700673 | 0.87 | CTSL (0.57) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL22449348 | 0.87 | CTSL (0.57) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL4346290 | 0.87 | CTSL (0.52) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL18855865 | 0.84 | CTSL (0.48) | CTSLCTSBCTSKEPHX2NPC1 | |
| SCHEMBL22008361 | 0.84 | CTSL (0.41) | CTSLCTSBCTSKEPHX2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960711-B1 | LIQUID-CRYSTAL DISPLAY | DAINIPPON INK & CHEMICALS (JP) | 2017-10-11 | — | — | EP | disclosed |