Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.32 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046298 | 0.90 | NPFFR1 (0.33) | NPFFR1NPFFR2L3MBTL1SIGMAR1KDM4E | |
| SCHEMBL10136052 | 0.83 | NPFFR1 (0.39) | NPFFR1NPFFR2L3MBTL1SIGMAR1KDM4E | |
| SCHEMBL10046524 | 0.83 | NPFFR1 (0.39) | NPFFR1NPFFR2L3MBTL1SIGMAR1KDM4E | |
| SCHEMBL15500314 | 0.80 | NPFFR1 (0.32) | NPFFR1NPFFR2L3MBTL1KDM4ELMNA | |
| SCHEMBL242270 | 0.78 | L3MBTL1 (0.41) | L3MBTL1SIGMAR1KDM4ELMNAGLA | |
| SCHEMBL19446207 | 0.77 | NPFFR1 (0.31) | NPFFR1NPFFR2KDM4ELMNAGLA | |
| SCHEMBL8240851 | 0.75 | SIGMAR1 (0.37) | L3MBTL1SIGMAR1KDM4ELMNAGLA | |
| SCHEMBL11519549 | 0.74 | L3MBTL1 (0.36) | L3MBTL1SIGMAR1KDM4EGLAGAA | |
| SCHEMBL409603 | 0.73 | CA12 (0.40) | NPFFR1NPFFR2SIGMAR1GAAMAPT | |
| SCHEMBL18867484 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350120-B1 | MULTILIGAND CONSTRUCTS | SEMIOTIK LLC (RU) | 2017-10-11 | — | — | EP | disclosed |