Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.58 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL15659681 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TRIM24TRIM33CFTRGOPC | |
| Biphenyl SCHEMBL15656774 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TRIM24TRIM33CFTRGOPC | |
| Biphenyl SCHEMBL15658831 | 0.97 | TRIM24 (0.56) | ALDH1A1TRIM24TRIM33CFTRGOPC | |
| Biphenyl SCHEMBL15657385 | 0.89 | ALDH1A1 (0.60) | ALDH1A1CFTRGOPCMEN1KMT2A | |
| Cyclohexanone SCHEMBL28737564 | 0.86 | TRIM24 (0.69) | ALDH1A1TRIM24TRIM33MEN1KMT2A | |
| Cyclohexanone SCHEMBL4564591 | 0.86 | ALDH1A1 (0.79) | ALDH1A1TRIM24TRIM33CFTRGOPC | |
| Cyclopentanone SCHEMBL28251672 | 0.83 | TRIM24 (0.77) | ALDH1A1TRIM24TRIM33CFTRGOPC | |
| Cyclohexanone SCHEMBL28737489 | 0.82 | TRIM24 (0.55) | ALDH1A1TRIM24TRIM33CFTRGOPC | |
| Biphenyl SCHEMBL27725627 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CFTRGOPCMEN1KMT2A | |
| Naphthalene SCHEMBL28272739 | 0.81 | TRIM24 (0.61) | ALDH1A1TRIM24TRIM33MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114574883-A | Method for deoxidizing, hydrogenating and deuterating alpha, beta-unsaturated aldehyde ketone into corresponding olefin and deuterated olefin | 南京中医药大学 | 2022-06-03 | — | — | CN | disclosed |
| EP-2735581-B1 | COMPOSITION AND POLYMER | ASAHI CHEMICAL IND (JP) | 2021-07-14 | — | — | EP | disclosed |
| CN-112375038-A | Preparation method of dibenzozepine | 山东嘉成医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-107573212-B | Synthesis method of trans-4-alkyl cyclohexyl benzene structure liquid crystal intermediate and monomer | 宁夏中星显示材料有限公司 | 2020-08-04 | — | — | CN | disclosed |
| US-9738757-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20160222168-A1 | Composition and Polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-08-04 | — | — | US | disclosed |
| US-9334371-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-05-10 | — | — | US | disclosed |
| EP-2735581-A1 | COMPOSITION AND POLYMER | Asahi Kasei Chemicals Corporation (JP) | 2014-05-28 | — | — | EP | disclosed |
| US-20140121293-A1 | Composition and Polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-05-01 | — | — | US | disclosed |
| EP-2507215-A1 | DIPHENYL AZEPINE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067219-A1 | DIPHENYL AZEPINE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| US-20110136787-A1 | DIPHENYL AZEPANE, DIAZEPANE AND OXAZEPANE DERIVATIVES AND USES THEREOF | SCHOENFELD RYAN CRAIG | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136787-A1 | DIPHENYL AZEPANE, DIAZEPANE AND OXAZEPANE DERIVATIVES AND USES THEREOF | PTGDR2, PTGDR, TBXA2R | ALDH1A1 1013/4885TRIM24 3852/4885TRIM33 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.