SCHEMBL19447355

SCHEMBL19447355

CSNc1ccc(Cl)cc1C(=O)N1CCCCC1c1cc2nc(N3CCCC3)c(C)cn2n1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 6/20 0.36
HCRTR2 O43614 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22788726 0.94 CCKBR (0.35) HCRTR1HCRTR2
SCHEMBL22788699 0.91 HRH4 (0.34) HCRTR1HCRTR2
SCHEMBL22788725 0.91 HCRTR1 (0.33) HCRTR1HCRTR2
SCHEMBL19447449 0.91 HCRTR1 (0.34) HCRTR1HCRTR2
SCHEMBL19447406 0.91 HPGD (0.33) HCRTR1HCRTR2
SCHEMBL22788715 0.91 HSP90AA1 (0.37)
SCHEMBL21279567 0.90 IRAK4 (0.34) HCRTR1HCRTR2
SCHEMBL12074690 0.88 MAPT (0.39)
SCHEMBL21279601 0.88 F10 (0.37) HCRTR1HCRTR2
SCHEMBL19447583 0.88 HCRTR1 (0.35) HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021050612-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2021-03-18 WO disclosed
WO-2020252396-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2020-12-17 WO disclosed
EP-2794611-B1 PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS GILEAD SCIENCES INC (US) 2017-10-11 EP disclosed