Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22788725 | 0.96 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL19447355 | 0.90 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL21279833 | 0.90 | IRAK4 (0.34) | IRAK4PIM1CDK2FLT4CSNK2A1 | |
| SCHEMBL2738059 | 0.90 | IRAK4 (0.34) | IRAK4PIM1CDK2FLT4CSNK2A1 | |
| SCHEMBL15317071 | 0.90 | IRAK4 (0.34) | IRAK4PIM1CDK2FLT4CSNK2A1 | |
| SCHEMBL22788699 | 0.89 | HRH4 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL19447449 | 0.87 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL2738155 | 0.86 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL22788702 | 0.85 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL22788726 | 0.84 | CCKBR (0.35) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838900-B1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-08-21 | — | — | EP | disclosed |