Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451779 | 0.89 | STING1 (0.48) | STING1CYP3A4 | |
| SCHEMBL28614903 | 0.89 | STING1 (0.48) | STING1CYP3A4 | |
| SCHEMBL24611738 | 0.88 | STING1 (0.49) | STING1CYP3A4 | |
| SCHEMBL22121384 | 0.83 | STING1 (0.63) | STING1CYP3A4 | |
| SCHEMBL28941702 | 0.83 | STING1 (0.63) | STING1CYP3A4 | |
| SCHEMBL23077541 | 0.82 | STING1 (0.57) | STING1CYP3A4 | |
| SCHEMBL22121390 | 0.82 | STING1 (0.57) | STING1CYP3A4 | |
| SCHEMBL22121334 | 0.81 | STING1 (0.50) | STING1CYP3A4 | |
| SCHEMBL22121353 | 0.80 | STING1 (0.46) | STING1CYP3A4 | |
| SCHEMBL20876512 | 0.80 | STING1 (0.51) | STING1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017175147-A1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-10-12 | — | — | WO | disclosed |