Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451779 | 1.00 | STING1 (0.48) | STING1CYP3A4 | |
| SCHEMBL24467471 | 0.90 | STING1 (0.47) | STING1 | |
| SCHEMBL19451814 | 0.89 | STING1 (0.48) | STING1CYP3A4 | |
| SCHEMBL24611738 | 0.88 | STING1 (0.49) | STING1CYP3A4 | |
| SCHEMBL19451781 | 0.85 | STING1 (0.45) | STING1 | |
| SCHEMBL22121384 | 0.83 | STING1 (0.63) | STING1CYP3A4 | |
| SCHEMBL28941702 | 0.83 | STING1 (0.63) | STING1CYP3A4 | |
| SCHEMBL23077541 | 0.82 | STING1 (0.57) | STING1CYP3A4 | |
| SCHEMBL22121390 | 0.82 | STING1 (0.57) | STING1CYP3A4 | |
| SCHEMBL22121334 | 0.81 | STING1 (0.50) | STING1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549110-A | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-109608443-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109071514-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-06 | — | — | CN | disclosed |