SCHEMBL19451978

SCHEMBL19451978

Brc1cc(Br)c(OC2C=CCC2)c(Br)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.33
THRB P10828 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9146672 0.89
SCHEMBL10549295 0.78 CYP3A4 (0.33) THRATHRB
SCHEMBL10544833 0.78 CYP3A4 (0.33) THRATHRB
SCHEMBL9152379 0.76
SCHEMBL9145109 0.76
SCHEMBL9152541 0.68 NPY1R (0.32)
SCHEMBL10543863 0.63
SCHEMBL538101 0.62
SCHEMBL11503080 0.62 LTA4H (0.43)
SCHEMBL9146115 0.61 HTR1A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017174439-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) 2017-10-12 WO disclosed