SCHEMBL19452811

SCHEMBL19452811

Clc1ccc2c3c(ccc2c1)SC(c1ccccc1)N3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.37
IDO1 P14902 1/20 0.36
MECP2 P51608 1/20 0.35
MBD2 Q9UBB5 1/20 0.35
ALDH1A1 P00352 4/20 0.35
MAPT P10636 3/20 0.35
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
LMNA P02545 2/20 0.35
NPC1 O15118 1/20 0.35
CYP19A1 P11511 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAOA P21397 1/20 0.35
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
NOX1 Q9Y5S8 1/20 0.33
HPGD P15428 3/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18544961 0.91 CYP2A6 (0.34) CYP2A6IDO1MECP2MBD2ALDH1A1
SCHEMBL19452556 0.81 MEN1 (0.34) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL23018228 0.80 NR1H4 (0.34) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL19452539 0.80 MEN1 (0.33) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL19452560 0.78 ALDH1A1 (0.39) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL23018313 0.78 HSD17B1 (0.33) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL22418184 0.76 TYMS (0.34) ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL19452557 0.76 KDM4E (0.39) MECP2MBD2ALDH1A1MAPTKDM4E
SCHEMBL18544839 0.74 ALDH1A1 (0.36) ALDH1A1MEN1KMT2ANPC1HPGD
SCHEMBL18814755 0.73 MEN1 (0.32) ALDH1A1MAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017175986-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-10-12 WO disclosed