Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661856 | 0.85 | L3MBTL1 (0.38) | PKMLMNAL3MBTL1HSP90AB1HTT | |
| SCHEMBL22011296 | 0.85 | KDM4E (0.35) | PKMLMNAL3MBTL1HSP90AB1HTT | |
| SCHEMBL23094652 | 0.78 | LMNA (0.37) | PKMLMNAL3MBTL1HSP90AB1HTT | |
| SCHEMBL18304964 | 0.78 | KMT2A (0.38) | PKMLMNAL3MBTL1HSP90AB1HTT | |
| SCHEMBL12705664 | 0.77 | HSP90AB1 (0.34) | HSP90AB1HTT | |
| SCHEMBL12661853 | 0.73 | L3MBTL1 (0.42) | LMNAL3MBTL1HSP90AB1HTTMAPT | |
| SCHEMBL15904085 | 0.73 | HSP90AB1 (0.41) | HSP90AB1ABCB1GAAKMT2A | |
| SCHEMBL8513029 | 0.73 | LMNA (0.38) | PKMLMNAL3MBTL1HSP90AB1HTT | |
| SCHEMBL26660089 | 0.73 | KDM4E (0.34) | PKMLMNAL3MBTL1HSP90AB1HTT | |
| SCHEMBL16189021 | 0.73 | TLR8 (0.35) | LMNAKDM4EMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176812-A1 | cGAS ANTAGONIST COMPOUNDS | IMMUNE SENSOR, LLC (US) | 2017-10-12 | — | — | WO | disclosed |