Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456736 | 0.86 | SLC22A12 (0.47) | SLC22A12 | |
| SCHEMBL19456710 | 0.84 | SSTR4 (0.42) | SLC22A12SSTR4CYP26A1PLCG1 | |
| SCHEMBL19456737 | 0.82 | SLC22A12 (0.36) | SLC22A12CYP26A1PLCG1 | |
| SCHEMBL19456817 | 0.80 | SLC22A12 (0.43) | SLC22A12PLCG1 | |
| SCHEMBL19456698 | 0.79 | ALDH1A1 (0.34) | CNR2GAA | |
| SCHEMBL19456704 | 0.78 | MALT1 (0.35) | SLC22A12CNR2 | |
| SCHEMBL19456713 | 0.77 | SLC22A12 (0.33) | SLC22A12CNR2 | |
| SCHEMBL19456912 | 0.75 | SLC22A12 (0.53) | SLC22A12PLCG1 | |
| SCHEMBL19456820 | 0.71 | SLC22A12 (0.53) | SLC22A12SSTR4PLCG1 | |
| SCHEMBL19456725 | 0.70 | CYP1A2 (0.37) | SLC22A12CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173965-A1 | NOVEL URAT1 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2017-10-12 | — | — | WO | disclosed |