Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | CIT | O14578 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976556 | 0.79 | EPHX2 (0.42) | FFAR2EPHX2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL18964090 | 0.78 | KDM4E (0.46) | FFAR2EPHX2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL7091214 | 0.78 | LMNA (0.50) | EPHX2DEGS1HDAC3HDAC4HDAC1 | |
| SCHEMBL25319854 | 0.76 | EPHX2 (0.43) | FFAR2EPHX2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL19111007 | 0.76 | NTRK1 (0.39) | CITTRPA1P2RX7HDAC3HDAC4 | |
| SCHEMBL1428278 | 0.75 | EPHX2 (0.44) | FFAR2EPHX2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL13024156 | 0.75 | FFAR2 (0.58) | FFAR2EPHX2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL25332354 | 0.75 | FFAR2 (0.44) | FFAR2EPHX2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL18969633 | 0.74 | FFAR2 (0.42) | FFAR2EPHX2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL19111000 | 0.73 | LMNA (0.58) | FFAR2CITDEGS1NAMPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176040-A1 | HETEROCYCLIC COMPOUND DECOMPOSING RAS AND USES THEREOF | 연세대학교 산학협력단 | 2017-10-12 | — | — | WO | disclosed |