Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11909062 | 0.85 | MAPT (0.46) | MAPTL3MBTL1ALDH1A1MGLLCRHBP | |
| SCHEMBL11909063 | 0.85 | MAPT (0.46) | MAPTL3MBTL1ALDH1A1MGLLCRHBP | |
| SCHEMBL1161470 | 0.82 | ALDH1A1 (0.47) | ALDH1A1DPP4DPP7MEN1LMNA | |
| SCHEMBL17171327 | 0.82 | ALDH1A1 (0.47) | ALDH1A1DPP4DPP7MEN1LMNA | |
| SCHEMBL1161469 | 0.82 | ALDH1A1 (0.47) | ALDH1A1DPP4DPP7MEN1LMNA | |
| SCHEMBL1161473 | 0.82 | ALDH1A1 (0.47) | ALDH1A1DPP4DPP7MEN1LMNA | |
| SCHEMBL27610824 | 0.82 | MAPT (0.48) | MAPTL3MBTL1ALDH1A1MGLLCYSLTR2 | |
| SCHEMBL1161626 | 0.78 | MEN1 (0.49) | MAPTDPP4DPP7MEN1LMNA | |
| SCHEMBL1161624 | 0.78 | MEN1 (0.49) | MAPTDPP4DPP7MEN1LMNA | |
| SCHEMBL15134836 | 0.78 | MEN1 (0.49) | MAPTDPP4DPP7MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170291955-A1 | BISPECIFIC HER2 ANTIBODIES | ASTRAZENECA UK LIMITED (GB) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291955-A1 | BISPECIFIC HER2 ANTIBODIES | ERBB2, EGFR, ERBB3 | MAPT 1139/4885L3MBTL1 4466/4885ALDH1A1 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.