SCHEMBL11909062

SCHEMBL11909062

CCCCCCCCCCCCCCCCCCOC(=O)C(N)Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ ALDH1A1 P00352 4/20 0.46
▸ MGLL Q99685 1/20 0.45
▸ MC4R P32245 1/20 0.45
▸ CRHBP P24387 1/20 0.44
▸ CRHR2 Q13324 1/20 0.44
▸ KCNH2 Q12809 1/20 0.44
▸ ESR1 P03372 1/20 0.43
▸ EPHX1 P07099 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ CACNA1F O60840 1/20 0.43
▸ CACNA1D Q01668 1/20 0.43
▸ CACNA1S Q13698 1/20 0.43
▸ CACNA1C Q13936 1/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ TYR P14679 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11909063 1.00 MAPT (0.46) MAPTL3MBTL1ALDH1A1MGLLMC4R
SCHEMBL27610824 0.87 MAPT (0.48) MAPTL3MBTL1ALDH1A1MGLLCRHBP
SCHEMBL909809 0.85 ALDH1A1 (0.44) MAPTL3MBTL1ALDH1A1MGLLMC4R
SCHEMBL19457418 0.85 MAPT (0.42) MAPTL3MBTL1ALDH1A1MGLLCRHBP
SCHEMBL1068871 0.84 MAPT (0.50) MAPTL3MBTL1ALDH1A1MC4RCRHBP
SCHEMBL1859542 0.84 MAPT (0.50) MAPTL3MBTL1ALDH1A1MC4RCRHBP
SCHEMBL11906658 0.83 ALDH1A1 (0.58) MAPTALDH1A1KCNH2LMNATYR
SCHEMBL5250954 0.83 SLC7A5 (0.51) MAPTALDH1A1ESR1LMNATYR
SCHEMBL7744532 0.83 SLC7A5 (0.51) MAPTALDH1A1ESR1LMNATYR
SCHEMBL6131701 0.83 TSHR (0.49) MAPTALDH1A1MC4RLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-06-23 — — US disclosed
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2020-05-28 — — US disclosed
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-02-04 — — US disclosed
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
EP-2673259-B1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-04-11 — — EP disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 — — US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
EP-2673259-A2 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM Bezwada Biomedical, LLC (US) 2013-12-18 — — EP disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
WO-2012109535-A2 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-08-16 — — WO disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 MAPT 4543/4885L3MBTL1 1482/4885ALDH1A1 2903/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MAPT 4398/4885L3MBTL1 1396/4885ALDH1A1 3569/4885
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MAPT 4398/4885L3MBTL1 1396/4885ALDH1A1 3569/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MAPT 4398/4885L3MBTL1 1396/4885ALDH1A1 3569/4885
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 MAPT 4398/4885L3MBTL1 1396/4885ALDH1A1 3569/4885
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 MAPT 4398/4885L3MBTL1 1396/4885ALDH1A1 3569/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MAPT 4398/4885L3MBTL1 1396/4885ALDH1A1 3569/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MAPT 4398/4885L3MBTL1 1396/4885ALDH1A1 3569/4885
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 MAPT 4398/4885L3MBTL1 1396/4885ALDH1A1 3569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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