Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | ERN1 | O75460 | 3/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.42 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269268 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ERN1TSHRKDM4ETDP1 | |
| SCHEMBL31474876 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ERN1TSHRKDM4ETDP1 | |
| SCHEMBL736351 | 0.81 | POLB (0.50) | ALDH1A1ERN1TSHRKDM4ETDP1 | |
| SCHEMBL29521638 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ERN1PRKDCTSHRKDM4E | |
| SCHEMBL195007 | 0.79 | ERN1 (0.58) | ALDH1A1ERN1PRKDCTLR2TLR1 | |
| SCHEMBL10541475 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ERN1PRKDCTSHRKDM4E | |
| SCHEMBL30681224 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ERN1PRKDCTSHRKDM4E | |
| SCHEMBL12672533 | 0.77 | ALDH1A1 (0.53) | ALDH1A1ERN1PRKDCTSHRKDM4E | |
| SCHEMBL148284 | 0.77 | PRKDC (0.48) | ALDH1A1ERN1PRKDCTSHRKDM4E | |
| SCHEMBL1620491 | 0.77 | ALDH1A1 (0.47) | ALDH1A1ERN1TSHRKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | ALDH1A1 2930/4885ERN1 800/4885PRKDC 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.