Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 8/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19799167 | 1.00 | P2RY1 (0.53) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL19459536 | 0.88 | ADORA3 (0.54) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL19799169 | 0.88 | ADORA3 (0.54) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL19464887 | 0.87 | P2RY1 (0.54) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL19799166 | 0.80 | HRH2 (0.49) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL19459932 | 0.80 | HRH2 (0.49) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL31350113 | 0.79 | ADORA3 (0.69) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL31350197 | 0.77 | ADORA3 (0.66) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL12269824 | 0.76 | ADORA3 (0.66) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 | |
| SCHEMBL12269821 | 0.76 | ADORA3 (0.56) | P2RY1ADORA3ADORA1HSP90AA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789131-B1 | Compounds and methods for treating neurological and cardiovascular conditions | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-17 | — | — | US | disclosed |