Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.54 |
| ▸ | HSP90B1 | P14625 | 6/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19799169 | 1.00 | ADORA3 (0.54) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL19459932 | 0.91 | HRH2 (0.49) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL19799166 | 0.91 | HRH2 (0.49) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL12269824 | 0.89 | ADORA3 (0.66) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL12269821 | 0.89 | ADORA3 (0.56) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL19799167 | 0.88 | P2RY1 (0.53) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL19459509 | 0.88 | P2RY1 (0.53) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL12269843 | 0.87 | ADORA3 (0.59) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL19415078 | 0.85 | P2RY1 (0.53) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL12269762 | 0.85 | P2RY1 (0.53) | ADORA3HSP90B1ADORA1ADORA2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789131-B1 | Compounds and methods for treating neurological and cardiovascular conditions | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-17 | — | — | US | disclosed |