Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CPS1 | P31327 | 11/20 | 0.40 |
| ▸ | FPR1 | P21462 | 5/20 | 0.36 |
| ▸ | FPR2 | P25090 | 4/20 | 0.36 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919958 | 0.88 | MC4R (0.40) | MC4R | |
| SCHEMBL1919904 | 0.82 | MC4R (0.45) | KDM4ESTAT3CPS1FPR1FPR2 | |
| SCHEMBL1948149 | 0.80 | MC4R (0.42) | CPS1FPR1FPR2MC4R | |
| SCHEMBL1945989 | 0.77 | MC4R (0.43) | KDM4ESTAT3CPS1FPR1FPR2 | |
| SCHEMBL15039514 | 0.74 | KDM4E (0.39) | KDM4ESTAT3CPS1FPR1FPR2 | |
| SCHEMBL1945899 | 0.71 | PDE10A (0.34) | BRD4 | |
| SCHEMBL1946750 | 0.71 | SIGMAR1 (0.45) | CPS1 | |
| SCHEMBL1946770 | 0.70 | DPP4 (0.47) | MC4R | |
| SCHEMBL1920198 | 0.69 | KMT2A (0.48) | CPS1FPR1FPR2MC4R | |
| SCHEMBL13493164 | 0.69 | MC4R (0.52) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | ANDREWS MARK DAVID | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | MC4R, CHRM4, GPR4 | KDM4E 804/4885STAT3 4055/4885CPS1 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.