Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 5/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.72 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.67 |
| ▸ | HTR2B | P41595 | 4/20 | 0.65 |
| ▸ | HTR2C | P28335 | 3/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19799168 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL26934921 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL26934179 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL5803728 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL25611948 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL5803724 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL23098401 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL19459442 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL19464849 | 0.90 | P2RY1 (0.63) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL19464924 | 0.90 | ADORA3 (0.70) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789131-B1 | Compounds and methods for treating neurological and cardiovascular conditions | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-17 | — | — | US | disclosed |