Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 5/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.72 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.67 |
| ▸ | HTR2B | P41595 | 4/20 | 0.65 |
| ▸ | HTR2C | P28335 | 3/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26934921 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL26934179 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL5803728 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL25611948 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL5803724 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL23098401 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL19459442 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL19459983 | 1.00 | P2RY1 (0.73) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL19464849 | 0.90 | P2RY1 (0.63) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A | |
| SCHEMBL19464924 | 0.90 | ADORA3 (0.70) | P2RY1ADORA3HSP90AA1HSP90B1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839615-B2 | Compounds and methods for treating addiction and related disorders | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20230165887-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-06-01 | — | — | US | disclosed |
| US-20180021363-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11839615-B2 | Compounds and methods for treating addiction and related disorders | ADORA2A, TAAR5, ADORA3 | P2RY1 113/4885ADORA3 3/4885HSP90AA1 3392/4885 |
| US-20180021363-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | TNNI3, CPT1B, TNNT2 | P2RY1 1828/4885ADORA3 778/4885HSP90AA1 1092/4885 |
| US-20230165887-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | TNNI3, CPT1B, TNNT2 | P2RY1 1828/4885ADORA3 778/4885HSP90AA1 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.